NK603 X T25 (OECD identifier: MON-ØØ6Ø3-6 x ACS-ZMØØ3-2) maize is an F1 hybrid resulting from the hybridization of the glyphosate herbicide-tolerant maize inbred NK603 (MON-ØØ6Ø3-6) with the glufosinate ammonium herbicide-tolerant maize inbred T25 (ACS-ZMØØ3-2). This stacked maize hybrid is a product of traditional plant breeding, and therefore is not automatically subject to regulation in all jurisdictions as are transgenic plants resulting from recombinant DNA technologies. Certain jurisdictions may request notification in advance of the release of a stacked hybrid, or may request information to conduct an environmental and food safety assessment. <br>The stacked hybrid NK603 X T25 expresses two novel proteins: CP4 EPSPS which confers tolerance to the herbicide glyphosate, and phosphinothricin N-acetyltransferase (PAT) which confers tolerance to the herbicide glufosinate ammonium. The CP4 EPSPS protein is produced by the <i>cp4 epsps</i> gene from NK603, and the PAT protein by the <i>pat</i> gene from T25. The novel traits of each parent line have been combined, through traditional plant breeding, to produce this new hybrid. For a full description of each parent line please refer to the individual product descriptions in the crop database for <a href="dbase.php?action=ShowProd&data=NK603&frmat=LONG"><b>NK603</b></a> and <a href="dbase.php?action=ShowProd&data=T14%2C+T25&frmat=LONG"><b>T25</b></a>.<br>The inserted genes and their gene products have a history of safe use, and have undergone review and approval by several regulatory agencies. No interactions among the gene products or negative synergistic effects are expected in the stacked hybrid. 