The Food and Drug Administration (FDA) is amending the food additive regulations to provide for the safe use of aminoglycoside 3'- phosphotransferase II (APH(3')II) as a processing aid in the development of new varieties of tomato, oilseed rape, and cotton. APH(3')II is a protein encoded by the kanamycin resistance (kanr) gene. This action is in response to a petition filed by Calgene, Inc.