One issue raised by the use of GMO in agriculture and food is the one of information of citizens and consumers. The article first deals with the significance and limits of various labelling strategies. According to the position of the European authorities a labelling which differentiates GMO products. One other position would be to identify the 'non-GMO' products. The article attempts to underscore the technical and economic regulations that could make credible a 'non-GMO' labelling.