'The safety and availability of high-quality food and animal feedstuffs are critical to populations worldwide,' saysTask Force Chair Professor Richard H. Phipps, School of Agriculture, Development and Policy, The University of Reading, Reading, United Kingdom. 'During the last decade the area of biotechnology-derived crops has increased dramatically from 4 to 90 million hectares/year, and crop varieties of corn, soybean, cotton, and canola are now widely used and are an important feedstuff in livestock production systems. It is essential, therefore, to consider the safety of meat, milk, and eggs obtained from animals fed crops derived from modern biotechnology.' Written and evaluated by a Task Force of international scientists?from the United Kingdom, Germany, the United States, and Brazil?this timely CAST Issue Paper has the following objectives: 1. To provide an overview of regulatory assessments of biotechnology-derived crops; and 2.To summarize the empirical data generated for assessing the safety of meat, milk, and eggs from animals fed biotechnology-derived crops that express agronomic input traits.  Animal products such as milk, meat, and eggs are significant sources of high-quality food for humans and represent approximately one-sixth of their food energy and one-third of their food protein on a global basis. Therefore, an important underlying tenet for the scientific assessment of the safety and nutritive value of crops derived from modern biotechnology is based on the question 'Is the biotechnology-derived crop as safe as a conventional crop?' Safety of Meat, Milk, and Eggs from Animals Fed Crops Derived from Modern Biotechnology provides evidence to support a strong affirmative response.