Raspberry bushy dwarf virus (RBDV) causes a significant reduction in yield and quality in raspberry and raspberry-blackberry hybrid.  Genetic modifications were made to 'Meeker' red raspberries to impart RBDV resistance.  The RBDV-resistant transgenic and wild type 'Meeker' plants were grown in Oregon and Washington, and the fruits were harvested in the 2004 and 2005 growing seasons.  Year-to-year and site-to-site variations were observed for the °Brix and titratable acidity, with Oregon raspberries having slightly higher °Brix and lower titratable acidity than Washington raspberries.  Twenty-nine volatile compounds were quantified using stir bar sorptive extraction (SBSE) paired with gas chromatography-mass spectrometry (GC-MS).  There were very few differences in volatile concentrations between the transgenic varieties and the wild type 'Meeker'.  Much larger variations were observed between sites and harvest seasons.  Raspberries grown in Oregon appeared to have higher concentrations of ä-octalactone, ä-decalactone, geraniol, and linalool.  Chiral analysis of á-ionone, á-pinene, linalool, terpinen-4-ol, ä-octalactone, and ä-decalactone demonstrated a much higher percentage of one isomer over the other, particularly á-ionone, á-pinene, ä-octalactone, and ä-decalactone, with more than 90% of one isomer, while a racemic mixture was observed for linalool.  The isomeric analysis revealed very little variation between varieties, locations, or years.  The flavor compounds tested in this study did not show any difference between the transgenic lines and the wild type 'Meeker' raspberry.