Russet Burbank potato plants which resist damage by Colorado potato beetle (CPB) have been developed through Agrobacterium-mediated transformation.  The CPB resistant potato plants produce two additional proteins, the Bacillus thuringiensis ssp. tenebrionis protein which confers resistance to CPB and the neomycin phosphotransferase II protein which serves as a selectable marker during the plant transformation process.  Extensive studies have been performed to assess the environmental and food safety of the CPB resistant potatoes to gain regulatory approval for commercialization of potato varieties with this new trait.  Data derived from the studies have confirmed the safety of the newly introduced proteins and demonstrated that the presence of these proteins and the process used to produce these plants did not alter the quality, composition or safety of the tubers from CPB resistant plants as compared to commercial Russet Burbank potatoes.